STRUCTURE-ACTIVITY RELATIONSHIPS

Structure-activity relationships (SAR) analysis forms the bedrock in drug discovery. By systematically modifying the chemical structure of a lead compound and measuring the resulting biological activity, researchers determine the key structural features responsible for efficacy. This knowledge guides further design of novel therapeutic agents with

The management of chronic pain often involves a multi-faceted approach, incorporating pharmacological interventions designed to modulate various physiological pathways involved in pain perception and transmission. Commonly employed drug classes include nonsteroidal anti-inflammatory drugs (NSAIDs), which exert their pain-relieving effects by inhibi